Flow Evidence

In October 2024, the largest clinical trial into tDCS in the UK and US was published by the authoritative Nature Medicine.

Patients who used Flow for 10-weeks were about twice as likely to see their depression go into remission than those in a control group who performed the same procedure with the current switched off.

The placebo-controlled RCT is considered the gold standard method for evaluating efficacy and was carried out by Kings College London, the University of East London and UTHealth Houston.

Source: Woodham, R.D., Selvaraj, S., Lajmi, N. et al. Nat Med (2024).

Nature Medicine Article →

Used by the NHS GPs, Psychiatrists, Postnatal and Crisis teams

Since March 2023, Flow has been offered to NHS patients. You can access a Flow trial on the NHS if you live in Northamptonshire, Leicestershire or West London and meet the qualifying criteria. Each NHS service has independently published a paper on Flow, including the Crisis team who saw up to a 75% drop in suicidal ideation.

Independent NHS Studies →

20+ independent clinical trials on tDCS Proven to have a definite effect on treating depression

There are now over 20 large, high quality Randomised Controlled Clinical Trials (RCTs) on tDCS (the technology Flow uses). Several meta-analyses of these trials have concluded that there is class A evidence (meaning definite effect) for the ability of tDCS to improve depression.

tDCS clinical research →

Feel better in 3 weeks, 77% report improvement

We have over 30,000 people using the Flow headset across Europe. Most people report positive results after 3 weeks; 77% see their depression score improve by at least 3 points. No one has reported a ‘serious’ side effect. Minor side effects include skin irritation and headaches.

n=14,383, self reported data

Depression-free by week 10, 57% were in remission

In the largest clinical trial into tDCS across the UK and US, people using Flow were about twice as likely to see their depression go into remission than those in a control group who performed the same procedure with the current switched off (using a placebo device). 57% of those using Flow were depression-free after 10 weeks.

Flow clinical trial →

Sleep better in less than 1 month, 1/2 of users experience sleep improvements in 3 weeks

A retrospective-study with over 6,000 people showed that: 1/3 of users reported they no longer had insomnia after just 1 week and 2/3 reported being insomnia free by 10 weeks. Reinforcing the importance and link between sleep and depression.

Flow sleep study →

Tackle more than just your low mood, 66%* feel an improvement with their anxiety

Anxiety and depression can be intertwined. 2/3's of our users felt an improvement of their anxiety after just 3 weeks of treating their depression with Flow.

*based on question 2 on the MADRSs Over 18,800 sample of real-world data